Unfortunately the San Diego Air & Space Museum provides little information with the photos in its collections. The vehicles makes it clear that this one was taken in Italy, and the Boeing 727 with '727' on the tail is a real smoking (pun intended) gun. It is demonstrator N7003U and we found information that it visited Fiumicino circa 1 October 1963. Photo from: San Diego Air & Space Museum
This photo was added on 4 January 2020, and has since been viewed 870 times.